Showing posts with label Cancer treatment. Show all posts
Showing posts with label Cancer treatment. Show all posts

Lung Cancer


Lung cancer is the most common cancer in men. It causes most deaths in Europe and America. Lung cancer morbidity is directly proportional to tobacco smoking. Due to asymptotic disease course, lung cancer is usually diagnosed too late, therefore, the treatment is extremely difficult and the prognosis is bad.

Causes

The main cause is tobacco smoking. The risk of lung cancer is highly related to the amount of cigarettes smoked during lifetime. Even passive smoking might double the risk. 95% of lung cancer cases are related to continuing smoking (including light cigarettes and pipes). Other cases are correlated to asbestos, chrome, genetic factors and air pollution.

Similar to other cancers, lung cancer consists of uncontrolled cell growth as a result of long-term contact to carcinogens, mentioned above. Damaged genes of a lung cell start uncontrolled cell growth. These cells form a tumor, infiltrate surrounding tissues, reach blood and lymphatic vessels and start metastasizing. The tumor disrupts the metabolic balance and consumes nutrients in the organism.

Symptoms

During the first stages, lung cancer is asymptotic. Later the symptoms depend on the localization of the tumor. Lung cancer might cause shortage of breath, coughing chest pain (rarely), pleuritis (pleurisy). Symptoms also depend on the metastasizing of lung cancer. Metastasizing to the mediastinum might cause hoarse voice, facial edema. Metastasizing to the central nervous system usually causes neurological symptoms, metastasizing to the bones causes severe pain etc. Advanced lung cancer often causes paraneoplastic syndrome (skin rash, hypotension, weight loss, etc.).

Diagnostics

Lung cancer is often detected accidentally by performing chest radiography. Otherwise, this test might be false negative. CT is much more informative and precise. If the tumor is endobronchial, bronchoscopy is usually performed. The diagnosis is verified with a biopsy (endobronchial, transbronchial or transcutaneous).

According to the results of biopsy and other tests, the tumor is classified (Non-small Cell Lung Carcinoma and Small Cell Lung Carcinoma) and staged (from IA to IV).

Treatment

The method of treatment depend on cancer’s cell type and stage. During stage I to II (sometimes in stage III) the main method of treatment is surgery. During stage III – IV chemotherapy and radiotherapy are performed. Symptomatic treatment is also essential.

Prognosis

Prognosis of lung cancer depends on cancer’s type and how far it has spread. Non-small Cell Lung Carcinoma usually has a better prognosis than Small Cell Lung Carcinoma.

Doctors Prove This Test Can Give Healthy People Cancer


The Nordic Cochrane Center has put out a leaflet that every woman should read, explaining the potential benefits and potential harms of mammographyi.

They point out that recent studies suggest mammography screening is not effective in reducing your risk of dying from breast cancer.

And in fact, screening creates breast cancer patients out of healthy women who would never have developed symptoms.

Treatment of these healthy women increases their risk of dying from heart disease and, yes, cancer itself.

According to the Nordic Cochrane Center:

“It therefore no longer seems reasonable to attend for breast cancer screening.

In fact, by avoiding going to screening, a woman will lower her risk of getting a breast cancer diagnosis.”

I highly recommend reading the report in its entiretyii, as it contains a number of enlightening tidbits that may help you make a more informed decision.

For example, after systematically reviewing the randomized trials of mammography, the authors concluded that:

“If 2,000 women are screened regularly for 10 years, one will benefit from screening, as she will avoid dying from breast cancer because the screening detebted the cancer earlier.

Since these trials were undertaken, treatment of breast cancer has improved considerably.

Women today also seek medical advice much earlier than previously, if they have noted anything unusual in their breasts…

Because of these improvements, screening is less effective today and newer studies suggest that mammography screening is no longer effective in reducing the risk of dying from breast cancer.”

… Since it is not possible to tell the difference between the dangerous and the harmless cell changes and cancers, all of them are treated.

Therefore, screening results in treatment of many women for a cancer disease they do not have, and that they will not get. Based on the randomized trials, it appears that:

If 2,000 women are screened regularly for 10 years, 10 healthy women will be turned into cancer patients and will be treated unnecessarily. These women will have either a part of their breast or the whole breast removed, and they will often receive radiotherapy, and sometimes chemotherapy. Treatment of these healthy women increases their risk of dying, e.g. from heart disease and cancer.”

So, to recap, in order for mammographic breast screening to save ONE woman’s life:

2,000 women must be screened for 10 years
200 women will get false positives, and
10 will receive surgery and/or chemotherapy even though they do not actually have cancer

Cochrane Conclusions Confirmed…

A couple of researchers at the University of Southampton set out to “assess the claim in a Cochrane review that mammographic breast cancer screening could be doing more harm than good.”

Their findings were published in the British Medical Journal in December last yeariii. By combining life years gained from screening with losses of quality of life from false positive diagnoses and surgery, the authors agreed with the Cochrane assessment, concluding that mammograms may indeed have “caused net harm for up to 10 years after the start of screening.”

ABC News reported on this findingiv:

“The default is to assume that screening must be good; catching something early must be good,” said James Raftery, professor of health technology assessment at the University of Southampton, U.K., and lead author of the review. “But if a woman has an unnecessary mastectomy, or chemotherapy or radiation, that’s a tragedy.

… “It’s difficult to balance the gain of one life against 200 false positives and 10 unnecessary surgeries,” said Raftery… The alternative is watchful waiting: delaying treatment until it’s clear whether a lump is truly a life-threatening tumor. But for woman faced with the words, “breast cancer,” watchful waiting is easier said than done…”

Have Dangerous Cancer Screening Devices Been Approved?

Based on information straight from the horse’s mouth, as it were, the answer to that question appears to be yes. Doctors and scientists at the U.S. Food and Drug Administration (FDA) Office of Device Evaluation have in fact warned Congress that the agency was approving medical devices that posed unacceptable risks to patients. As early as 2007, concerned employees in this department began making internal complaints about a dozen different radiological devices about to be approved despite lack of proof of effectiveness.

They stated they were concerned that millions of patients’ lives would be put at risk from these devices.

This included three devices that risked missing signs of breast cancer, and several colon cancer screening devices that employed such heavy doses of radiation they risked causing cancer in otherwise healthy people. In the case of a computer-aided imaging device for breast cancer screening, the scientists recommended against approval no less than three times, but after the third rejection, a senior manager, Donna-Bea Tillman, suddenly approved the device.

Subsequently, over the course of two years, the FDA secretly monitored the personal e-mail of nine whistleblowers within the department of device evaluations, and tried to launch an investigation against them, accusing them of “undermining the integrity and mission of the FDA” and illegal disclosure of trade secrets. Six of the monitored scientists and doctors recently filed a lawsuit against the FDA, charging that the agency violated their constitutional rights to privacy by monitoring lawful activity in personal email accounts, and using that information to harass and ultimately relieve some of them of their positions.

One of the key players in this ongoing drama is Jeffrey Shuren, director of the FDA’s Center for Devices and Radiological Health, who has repeatedly requested action be taken against the employees in question. Shuren is also the official who oversees mercury dental fillings, which they have been fraudulently referring to as ‘silver fillings.’ Shuren promised to make an announcement aboutdental amalgam by the end of 2011, but with just minutes left in the work year, the FDA conceded that no announcement was forthcoming, and maybe never will…

The FDA’s own doctors and scientists have called for a complete overhaul of the agency due to “deep-rooted systemic corruption at the highest levels.” There’s no doubt they know what they’re talking about. And there’s a lot of damning information out there that can, and eventually will, be used to call for a congressional hearing on the mammography cover-up.

Mammograms Often Lead to Unnecessary Treatments

In 1974, the National Cancer Institute (NCI) was warned by professor Malcolm C. Pike at the University of Southern California School of Medicine that a number of specialists had concluded that “giving a women under age 50 a mammogram on a routine basis is close to unethical.”

The warning fell on deaf ears, and the long-held conventional medical advice has been for women to get an annual mammogram once they hit 40. A couple of years ago, the U.S. Preventive Services Task Force decided to alter their mammogram recommendation, advising women under the age of 50 to avoid mammograms, and limit them to every other year after the age of 50. The revision caused outrage among many cancer organizations. What was overlooked, however, was the reasoning behind the Task Force’s decision to change their recommendation.

The prior advice was given in 2002, before a host of new research came out showing the problems of over diagnosis, including false positives. And as discussed above, it’s really hard to justify harming 10 women with surgery and toxic chemotherapy treatment, just to save the life of one woman…

Part of the problem is that cancer diagnosing is not really a cut and dry process. If a mammogram detects an abnormal spot in a woman’s breast, the next step is typically a biopsy. This involves removing a small amount of tissue from the breast, which is then looked at by a pathologist under a microscope to determine if cancer is present. However, early stage cancer like ductal carcinoma in situ, or D.C.I.S., can be very hard to diagnose, and pathologists have a wide range of experience and expertise. There are actually NO diagnostic standards for D.C.I.S., and there are no requirements that the pathologists doing the readings have specialized expertise…

Increase in Breast Cancer Actually Found to be Due to Over-Diagnosis!

In other recent news, a Norwegian follow-up study that looked at 14 years of mammography screening in Norway concluded that the increased incidence of breast cancer observed in that period was, again, simply due to over-diagnosis.v According to the authors:

“In 2004 we wrote in Tidsskriftet that mammography screening resulted in massive over-diagnosis and over-treatment of breast cancer. Our study was criticized because we had only five years of follow-up time and did not take account of the fact that increased use of hormone replacement therapy could lead to more breast cancer.

We have now been screening women for 14 years, and during a period when the use of hormones has fallen by 70 percent.

… The number of new cases of breast cancer in the period increased from around 2,000 to 2,750. About 300 cases of ductal carcinoma in situ (DCIS) were also diagnosed. Today a total of some 1,050 more women have been diagnosed than before screening started. Our calculations indicate that in the absence of screening, around 800 of these women would never have become breast cancer patients. The figures from 14 years of mammography screening indicate that all increase in the incidence of breast cancer is due to over-diagnosis: findings of tumors that in the absence of screening would never have given rise to clinical illness.”

When it Comes to Cancer, Getting Second and Third Opinions is Advisable…

Once you delve into the research, you find that the issue of mammography is not as clear-cut as conventional medical wisdom would have you believe. There are many risks, and according to some studies, these risks will outweigh the potential benefits for many women. And, it appears very clear that more women are harmed by it than are saved…

In the event you do receive a mammogram and a biopsy and are diagnosed with D.C.I.S. or another form of early stage breast cancer, I recommend getting a second, and possibly third and even fourth, opinion. I cannot stress this enough, as the false positive rates are so high, and the diagnostic criteria so subjective. Before you make any decision on treatment, and definitely before you decide to have surgery or chemotherapy, make sure your biopsy results have been reviewed by a breast specialist who is knowledgeable and experienced in the field.

How to Dramatically Cut Your Breast Cancer Risk

There are a number of lifestyle changes that can help prevent breast cancer from ever becoming a reality for you. For starters, we cannot discuss breast cancer without mentioning the importance of vitamin D. Vitamin D, a steroid hormone that influences virtually every cell in your body, is easily one of nature’s most potent cancer fighters. Receptors that respond to vitamin D have been found in nearly every type of human cell, from your bones to your brain. Your liver, kidney and other tissues can convert the vitamin D in your bloodstream into calcitriol, which is the hormonal or activated version of vitamin D.

Your organs then use it to repair damage, including that from cancer cells.

Vitamin D is actually able to enter cancer cells and trigger apoptosis or cancer cell death. When JoEllen Welsh, a researcher with the State University of New York at Albany, injected a potent form of vitamin D into human breast cancer cells, half of them shriveled up and died within days! vi

The vitamin D worked as well at killing cancer cells as the toxic breast cancer drug Tamoxifen, without any of the detrimental side effects and at a tiny fraction of the cost.

It is my impression that it is criminal malpractice not to recommend vitamin D and aggressively monitor a breast cancer patient’s vitamin D level to get it between 70 and 100 ng/ml. Vitamin D works synergistically with every cancer treatment I am aware of and has no adverse effects. According to one landmark study, some 600,000 cases of breast and colorectal cancers could be prevented each year if vitamin D levels among populations worldwide were increased. And that’s just counting the death toll for two types of cancer (it actually works against at least 16 different types)!

So please do watch my one-hour free lecture on vitamin D to find out what your optimal vitamin D levels should be … and how to get them there. This is one of the most important steps you can take to protect yourself from cancer.

Other Breast Cancer Prevention Musts

A healthy diet, regular physical exercise, appropriate sun exposure and an effective way to manage your emotional health are the cornerstones of just about any cancer prevention program, including breast cancer. But for breast cancer, specifically, you can take it a step further by also watching out for excessive iron levels. This is very common once women stop menstruating, and the extra iron works as a powerful oxidant, increasing free radicals and raising your risk of cancer. So if you are a post menopausal woman or have breast cancer you will certainly want to have your Ferritin level drawn. Ferritin is the iron transport protein and should not be above 80. So if it is elevated you can simply donate your blood to reduce it.

Further, the following lifestyle strategies will help to further lower your risk:

Improve Your Insulin Receptor Sensitivity. The best way to do this is to cut as much sugar, fructose and grains as possible from your diet, and make sure you have an optimized exercise program. Please don’t make the mistake of focusing on cardio to the exclusion of everything else. You can get some ideas from reviewing my video on exercise. (Although I did not mention stretching and flexibility work, such as yoga, in the video, it is a very important part of your exercise program. It will not affect insulin receptors but it will help prevent you from getting injured and stopping your other exercise.)
Maintain a healthy body weight. This will come naturally when you begin eating properly and exercising. It’s important to lose excess weight because estrogen, a hormone produced in fat tissue, may trigger breast cancer.
Get plenty of high quality animal-based omega-3 fats, such as krill oil. Omega-3 deficiency is a common underlying factor for cancer.
Avoid drinking alcohol, or limit your drinks to one a day for women.
Breastfeed exclusively for up to six months. Research shows this will reduce your breast cancer risk.
Avoid synthetic hormone replacement therapy. Breast cancer is an estrogen-related cancer, and according to a study published in the Journal of the National Cancer Institute, breast cancer rates for women dropped in tandem with decreased use of hormone replacement therapy. (There are similar risks for younger women who use oral contraceptives. Birth control pills, which are also comprised of synthetic hormones, have been linked to cervical and breast cancers.)

If you are experiencing excessive menopausal symptoms, you may want to consider bioidentical hormone replacement therapy instead, which uses hormones that are molecularly identical to the ones your body produces and do not wreak havoc on your system. This is a much safer alternative.
Avoid BPA, phthalates and other xenoestrogens. These are estrogen-like compounds that have been linked to increased breast cancer risk
Make sure you’re not iodine deficient, as there’s compelling evidence linking iodine deficiency with breast cancer. Dr. David Brownsteinvii, author of the book Iodine: Why You Need it, Why You Can’t Live Without it, is a proponent of iodine for breast cancer. It actually has potent anticancer properties and has been shown to cause cell death in breast and thyroid cancer cells. For more information, I recommend reading Dr. Brownstein’s book. I have been researching iodine for some time ever since I interviewed Dr. Brownstein as I do believe that the bulk of what he states is spot on. However, I am not at all convinced that his dosage recommendations are correct. I believe they are too high. I hope to publish some articles on this later this year with my recommendations.

Cervical Cancer treatment


Cervical cancer is a disease in which malignant (cancer) cells form in the tissues of the cervix.

The cervix is the lower, narrow end of the uterus (the hollow, pear-shaped organ where a fetus grows). The cervix leads from the uterus to the vagina (birth canal).

Cervical cancer usually develops slowly over time. Before cancer appears in the cervix, the cells of the cervix go through changes known as dysplasia, in which cells that are not normal begin to appear in the cervical tissue. Later, cancer cells start to grow and spread more deeply into the cervix and to surrounding areas.

Cervical cancer in children is rare. For more information, see the PDQ summary on Unusual Cancers of Childhood.

Human papillomavirus (HPV) infection is the major risk factor for development of cervical cancer.

Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. People who think they may be at risk should discuss this with their doctor.

Infection of the cervix with human papillomavirus (HPV) is the most common cause of cervical cancer. Not all women with HPV infection, however, will develop cervical cancer. Women who do not regularly have a Pap smear to detect HPV or abnormal cells in the cervix are at increased risk of cervical cancer.

Other possible risk factors include the following:

* Giving birth to many children.
* Having many sexual partners.
* Having first sexual intercourse at a young age.
* Smoking cigarettes.
* Oral contraceptive use ("the Pill").
* Weakened immune system.

There are usually no noticeable signs of early cervical cancer but it can be detected early with yearly check-ups.

Early cervical cancer may not cause noticeable signs or symptoms. Women should have yearly check-ups, including a Pap smear to check for abnormal cells in the cervix. The prognosis (chance of recovery) is better when the cancer is found early.

Possible signs of cervical cancer include vaginal bleeding and pelvic pain.

These and other symptoms may be caused by cervical cancer. Other conditions may cause the same symptoms. A doctor should be consulted if any of the following problems occur:

* Vaginal bleeding.
* Unusual vaginal discharge.
* Pelvic pain.
* Pain during sexual intercourse.

Tests that examine the cervix are used to detect (find) and diagnose cervical cancer.

The following procedures may be used:

* Pap smear: A procedure to collect cells from the surface of the cervix and vagina. A piece of cotton, a brush, or a small wooden stick is used to gently scrape cells from the cervix and vagina. The cells are viewed under a microscope to find out if they are abnormal. This procedure is also called a Pap test.
Pelvic exam. A doctor or nurse inserts one or two lubricated, gloved fingers of one hand into the vagina and presses on the lower abdomen with the other hand. This is done to feel the size, shape, and position of the uterus and ovaries. The vagina, cervix, fallopian tubes, and rectum are also checked.
* Endocervical curettage: A procedure to collect cells or tissue from the cervical canal using a curette (spoon-shaped instrument). Tissue samples may be taken and checked under a microscope for signs of cancer. This procedure is sometimes done at the same time as a colposcopy.

Certain factors affect prognosis (chance of recovery) and treatment options.

The prognosis (chance of recovery) depends on the following:

* The patient's age and general health.
* Whether or not the patient has a certain type of human papillomavirus.
* The stage of the cancer (whether it affects part of the cervix, involves the whole cervix, or has spread to the lymph nodes or other places in the body).
* The type of cervical cancer.
* The size of the tumor.

Treatment options depend on the following:

* The stage of the cancer.
* The size of the tumor.
* The patient's desire to have children.
* The patient’s age.

Treatment of cervical cancer during pregnancy depends on the stage of the cancer and the stage of the pregnancy. For cervical cancer found early or for cancer found during the last trimester of pregnancy, treatment may be delayed until after the baby is born.